Hyperthermic intraperitoneal chemotherapy (HIPEC) is a highly concentrated, heated chemotherapy treatment that is delivered directly to the abdomen during surgery.
Unlike systemic chemotherapy delivery, which circulates through the body, HIPEC delivers chemotherapy directly to cancer cells in the abdomen. This allows for higher doses of chemotherapy treatment. Heating the solution may improve the absorption of chemotherapeutic drugs by tumors and destroy microscopic cancer cells that remain the abdomen after surgery.
How it works
HIPEC is performed during surgery to remove visible tumors within the abdomen. After debulking, the surgeon administers the chemotherapy solution to penetrate and destroy cancer cells that remain in the abdomen after surgery. High doses of a sterile solution containing chemotherapy drugs are circulated throughout the abdomen, for up to two hours.
Once the hyperthermic intraperitoneal chemotherapy treatment is complete, the solution is drained from the abdomen and the incision is closed.
HIPEC is a treatment option for people who have advanced surface spread of cancer within the abdomen, without disease involvement outside of the abdomen.
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