Leukocyte-enriched platelet-rich plasma effectively and safely treated patients with lateral epicondylar tendinopathy in a recent study. In a randomized control trial, Allan K. Mishra, MD, of the orthopedic surgery department, Menlo Medical Clinical, Stanford University Medical Center, and colleagues studied 230 patients with chronic lateral epicondylar tendinopathy (tennis elbow) who were treated over 5 years at 12 centers. The patients, symptomatic for at least 3 months and unresponsive to conventional therapy, were divided into two groups: platelet-rich plasma recipients (PRP; n=116) or active controls (n=114). Venous whole blood at initiation was used to prepare the PRP that contained concentrated platelets and leukocytes.
Patients and investigators were masked throughout the study; patients had their extensor tendons needled with or without PRP after receiving local anesthetic. Patients were followed for up to 24 weeks.
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