Aryl Hydrocarbon Receptor May Play Role In Red Blood Cell Development

DCE448D003864B5783890EE8BC76D972Modulation of the aryl hydrocarbon receptor was associated with significant production of hematopoietic progenitor cells in vitro, according to study results.Several researchers from Boston and Philadelphia have demonstrated that the aryl hydrocarbon receptor may regulate the hematopoietic and immune systems during development in a cell-specific manner.

An in vitro model system that allows the production of primary human hematopoietic progenitor cells that have the capacity to differentiate into megakaryocyte- and erythroid-lineage cells facilitated the current study. Researchers aimed to determine whether aryl hydrocarbon receptor modulation could facilitate the expansion of progenitor cells and the differentiation of megakaryocyte and erythroid cells.

 

The full article is located at healio.com

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